Advancing analytical workflows for prohibited substance detection in equine athletes

March 18, 2020 at 16:00 GMT / 12:00 EDT / 09:00 PDT / 17:00 CET

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Advancing analytical workflows for prohibited substance detection in equine athletes

March 18, 2020 at 16:00 GMT / 12:00 EDT / 09:00 PDT / 17:00 CET

Overview

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Despite advances in analytical chemistry, it is becoming increasingly challenging to control prohibited substance abuse in equine athletes. One such challenge is the ever-increasing number of prohibited substances, which require large custom-made compound databases and mass spectral libraries to allow for screening and testing.

In this webinar, Professor Scott Stanley and Dr. Sophie Bromilow from the Equine Analytical Research Laboratory will discuss the software tools available, how these can be implemented during method development, data acquisition, and data analysis, and how software compatibility across platforms enables the use of the Method Editor tool to ultimately advance analytical workflows.

Here, Stanley and Bromilow will outline the development of a >440 compound screen, with a custom-built mass spectral library and compound database, including the transfer of this method from a Thermo Scientific™ Orbitrap Exploris™ 480 MS to a Thermo Scientific™ TSQ Altis™ mass spectrometer for confirmation. They will also demonstrate the integration of multiple software tools, including mzCloud, mzVault, and Thermo Scientific™ TraceFinder™ SW, for a holistic view of method development beyond analytical capabilities.

Learning objectives
  • Understand the analytical challenges of confidently detecting and identifying prohibited substances
  • Discover how integrated software tools can drive rapid method development from a discovery environment through to routine screening and confirmation
  • See how connected hardware platforms and software tools aid in method transfer and help to advance analytical workflows to combat the issues of prohibited substance detection
  • Better understand how a connected laboratory is now a reality and can help with small molecule compound identification and quantitation workflow deployment

Who should attend:
  • Researchers and leaders in academia, bio/pharma, clinical, forensic toxicology, and protein research, and any laboratories who are focused on both small molecule and protein identification and quantitation workflows where there is the need to transfer knowledge from research through to routine
  • Lab directors and industry experts who are responsible for setting new standards and, when needed, demonstrate success in challenging or high-profile work
  • Technology leaders responsible for the competitive edge while improving productivity and efficiency with highly trained operators
  • Principle scientists in screening and quantitative applications who need the best technology to advance their research discoveries and develop new testing methodologies


Presenters

Presenter
Professor Scott Stanley
Professor in Equine Toxicology and Pharmacology, Department of Veterinary Science and Director of the Equine Analytical Chemistry Laboratory
University of Kentucky
View Biography
Presenter
Dr. Sophie Bromilow
Scientist III at Equine Analytical Research Laboratory
University of Kentucky
View Biography
Presenter
Moderator: Charlie Carter
Associate Editor
SelectScience
View Biography